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Global Solid-phase Peptide Synthesis (SPPS) Market

avatar/IMG-10 by Foreclaro Global Research
2025 Aug, 12

According to the Foreclaro Global Research, the Global Solid-phase Peptide Synthesis (SPPS) Market size was valued at USD 401.5 million in 2024. The report “Global Solid-phase Peptide Synthesis (SPPS) Market By Product Type (Reagent {Protecting Reagents, Coupling Reagents, Cleavage Reagents}, Resins, Synthesis Equipment, Software for Automated SPPS Instruments), By Technology (Fmoc (Fluorenylmethyloxycarbonyl) Chemistry, Boc (tert-Butyloxycarbonyl) Chemistry, Others (Hybrid Methods)), By Application (Drug Discovery and Development, Vaccine Development, Therapeutic Peptides, Diagnostic Applications, Research & Academic Use, Cosmetic Peptides), By End User (Pharmaceutical and Biotechnology Companies, Contract Research Organizations (CROs), Academic & Research Institutes, Cosmetic Companies)- Industry Trends and Forecast to 2033” gives a detailed insight into current market dynamics and provides analysis on future market growth.

 

Solid-Phase Peptide Synthesis (SPPS) is a broadly used approach for generating peptides, which might be quick chains of amino acids with crucial roles in drug development, diagnostics, and biotechnology. Introduced with the aid of using Bruce Merrifield withinside the 1960s, SPPS revolutionized peptide synthesis with the aid of using allowing automated, sequential meeting of amino acids on an insoluble resin support. This approach gives blessings which include ease of purification, excessive yield, and compatibility with automation, making it perfect for excessive-throughput synthesis and pharmaceutical manufacturing. SPPS is the desired approach for generating complex, long-chain peptides utilized in healing packages like cancer, diabetes, and infectious diseases. It entails using defensive groups (like Fmoc or Boc), coupling reagents, and cleavage steps to construct peptides with excessive specificity and purity. The approach helps scalable and green production, critical for studies and industrial uses. With developing demand for peptide therapeutics, SPPS is still a cornerstone era in contemporary-day molecular biology and drug discovery.

 

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Global Solid-phase Peptide Synthesis (SPPS) Market Report Highlights

·         The global SPPS market was valued with a robust increase pushed via way of means of growing demand for peptide therapeutics and technological advancements.

·         Fmoc-primarily based totally SPPS dominates the marketplace because of its milder deprotection process, automation compatibility, and better performance as compared to Boc chemistry.

·         Reagents (protecting, coupling, cleavage) constitute the most important revenue-producing segment, accompanied via way of means of synthesis systems and resins.

·         Major use instances consist of drug discovery, healing peptide production, vaccine development, diagnostics, and beauty peptides.

·         Pharmaceutical and biotechnology groups lead the marketplace demand for, whilst CROs and educational institutes increasingly undertake SPPS for studies and development.

·         North America holds the most important marketplace share; however, Asia-Pacific is the fastest-developing region because of growing biotech investments and increasing peptide drug pipelines.

 

Foreclaro Global Research has segmented the Solid-phase Peptide Synthesis (SPPS) Market report based on Product Type, Technology, Application, End User, and region:

 

Solid-phase Peptide Synthesis (SPPS) Market, Product Type Outlook (Revenue - USD Million, 2020 - 2033)

Reagent

·         Protecting Reagent

·         Coupling Reagents

·         Cleavage Reagents

Resins

Synthesis Equipment

Software for Automated SPPS Instruments

 

Solid-phase Peptide Synthesis (SPPS) Market, Technology Outlook (Revenue - USD Million, 2020 - 2033)

Fmoc (Fluorenylmethyloxycarbonyl) Chemistry

Boc (tert-Butyloxycarbonyl) Chemistry

Others (Hybrid Methods)

 

Solid-phase Peptide Synthesis (SPPS) Market, Application Outlook (Revenue - USD Million, 2020 - 2033)

Drug Discovery and Development

Vaccine Development

Therapeutic Peptides

Diagnostic Applications

Research & Academic Use

Cosmetic Peptides

 

Solid-phase Peptide Synthesis (SPPS) Market, End user Outlook (Revenue - USD Million, 2020 - 2033)

Pharmaceutical and Biotechnology Companies

Contract Research Organizations (CROs)

Academic & Research Institutes

Cosmetic Companies

 

Solid-phase Peptide Synthesis (SPPS) Market, Regional Outlook (Revenue - USD Million, 2020 - 2033)

North America

·         United States

·         Canada

·         Mexico

 

Europe

·         United Kingdom

·         Germany

·         France

·         Spain

·         Italy

·         Rest of Europe

 

Asia Pacific

·         China

·         India

·         Japan

·         Australia

·         South Korea

·         Rest of Asia Pacific

 

Latin America

·         Brazil

·         Argentina

·         Rest of Latin America

 

Middle East & Africa

·         Saudi Arabia

·         South Africa

·         Rest of MEA

 

Global Solid-phase Peptide Synthesis (SPPS) Market Key Players

·         Thermo Fisher Scientific Inc.

·         Bachem Holding AG

·         CEM Corporation

·         Merck KGaA (MilliporeSigma)

·         GenScript Biotech Corporation

·         Biotage AB

·         AAPPTec, LLC

·         AnaSpec, Inc. (A Kaneka Company)

·         CSBio

·         PolyPeptide Group